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PAINCEPTOR PHARMA ANNOUNCES PATENT AWARDS FOR ITS LEAD DRUG DEVELOPMENT PROGRAMS

Expands Intellectual Property Portfolio for Potential Pain Drugs

Montreal, Canada - September 28, 2006 - PainCeptor Pharma Corp., a biopharmaceutical company focused on the development of novel therapeutics for the treatment of chronic and acute pain, today announced that it has been awarded a series of milestone patents for its two lead drug development programs, NGF (nerve growth factor) and ASIC (acid sensing ion channel) antagonists.

The new patents provide further independent validation of the unique and important nature of these novel mechanisms of action and of PainCeptor's leading-edge role as an innovator in the field of pain therapeutics.

The four patents granted PainCeptor are:


1. 'Neurotrophin Antagonists for the Treatment of Epilepsy, Alzheimer's Disease and Pain'' - patent allowed in Europe (#0930883) and Israel (#129475)

2. 'Method of Inhibiting Neurotrophin-Receptor Binding'' - patent issued in Australia (#781888)

3. “DNA Encoding a Human Proton-Gated Ion Channel and Uses Thereof'' - patent allowed in Europe (#EP-B-1025226)

4. “Method of Inhibiting Neurotrophin-Receptor Binding'' - US Divisional Patent allowed

These patents bring the total of PainCeptor's intellectual property portfolio to 39 issued patents; with an additional 45 patent applications under examination; and a further 10 provisional applications pending.

The new patents, together with those issued previously, provide broad protection for the proprietary drug candidates PainCeptor has developed for NGF and ASIC mediated disease conditions including;


• pain

• inflammatory disorders including gastrointestinal & genitourinary diseases

• circulatory & respiratory conditions, and

• a broad spectrum of neurological diseases

"We are delighted that the ground-breaking nature of our innovations continues to be recognized" commented Dr. Francine Gervais, Senior Vice-President, Pharmaceutical Development, “These new patents support our ongoing strategy to broaden the proprietary scope of our drug development platforms.”

About PainCeptor Pharma

PainCeptor Pharma is a biopharmaceutical company developing next generation therapeutic drugs for the treatment of chronic and acute pain. PainCeptor's resources are concentrated on some of the most promising, novel, yet scientifically validated therapeutic targets within the PNS (peripheral nervous system). By focusing on modulating target receptors in the PNS, PainCeptor expects to enhance the efficacy and avoid the many detrimental side effects associated with today's pain drugs which act primarily in the CNS. PainCeptor's development pipeline includes two lead antagonist programs, targeting NGF/p75-TrkA and ASIC1a, and a third antagonist program targeting ASIC3.

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For more information, please visit our website at www.PainCeptor.com or contact us at info@PainCeptor.com or (514) 337-5959